Frequently Asked Questions

What is FSA/ID ?

Learn about female sexual arousal and interest disorder

What are the ingredients in Zestra®?

PA-free borage seed oil, evening primrose oil, angelica extract, Coleus forskholii extract, theobromine, and the anti-oxidants vitamin C and vitamin E.

How do I apply Zestra®?

Watch the How to Apply Zestra video.

What ensures the quality of Zestra®?

Zestra® is made by scientists with only the highest quality ingredients under GMP (Good Manufacturing Practices) guidelines. Zestra® is expertly manufactured and packaged in a FDA-registered pharmaceutical and consumer products manufacturing facility.

How was Zestra® developed?

Zestra® was developed by a pharmacologist who was focused on finding ways to enhance women’s sexual satisfaction. Zestra® is the result of a thoughtful, detailed exploration of scientific research and concern for women. Recommended by doctors and women’s healthcare professionals, Zestra® has been established – in two clinical trials (**Read Zestra® Clinical Trials) – to improve women’s feelings of desire, arousal and sexual satisfaction.

How long has Zestra® been on the market?

Zestra® was first introduced in June 2002. The development of Zestra® stems from over 5 years of research performed by pharmaceutical researchers and sexual health experts.

Is Zestra® available to everyone?

Yes, Zestra® is an OTC that can be purchased in pharmacy or online at without a prescription.

Are there any guarantees that Zestra® will work for me?

As with any product, response can vary from person to person, with some more responsive than others. Any number of factors can affect sexual health and enjoyment such as environment, lifestyle, diet, hormone levels, age, relationship status or certain prescription medications. If you have questions about whether Zestra® is appropriate for you, talk with a healthcare professional who knows your personal medical history and therefore can determine if Zestra® is likely to work for you.

How does Zestra® compare to other products on the market?

Zestra® is hormone-free, glycerin-free, paraben-free and topically applied. Zestra® is not a typical “warming” product and does not contain L-arginine or other chemicals like the competition. It is the only product documented to increase a woman’s feelings of desire and arousal in a published peer-reviewed medical journal without any known interactions.

Is it safe to use a silicone vibrator or sex toy once Zestra® has been applied?

Zestra® is an oil-based product and is safe to use with silicone vibrators or sex toys. Please note that while it is completely safe to use Zestra® with silicone vibrators or sex toys, Zestra® should NOT be used with latex condoms. It is safe to use Zestra® with polyurethane condoms because the integrity of polyurethane condoms is not affected by oil-based products (like Zestra®).

Is it safe to use Zestra® during oral sex? 
Zestra® was specifically designed to increase female pleasure during foreplay, manual stimulation, vaginal intercourse and masturbation. The ingredients in Zestra® are derived from natural botanical ingredients that are often used in dietary supplements, and have well-established safety profiles. Zestra® is harmless if ingested. Make sure your partner doesn’t have allergies to any of the ingredients in Zestra®.

I have sensitive skin, can I still use Zestra®?

Zestra® is hormone-free, glycerin-free and paraben-free. Its formula was created for the most delicate areas. Zestra® is safe to use for all women as long as they use the product as prescribed. Do not use if you have a known hypersensitivity (allergy) to any of the ingredients in Zestra®. Do not use if you have any type of vaginal infection or irritation such as a yeast infection. If you believe you have a yeast infection, consult your healthcare professional for treatment and wait until the infection is resolved before using Zestra®.

Can I use Zestra® every day, more than once a day?

Zestra® can be used as often as needed and during every sexual experience, if desired.

What is Glide™ by Zestra®? Is it like Zestra®?

Glide™ is a paraben-free, water-based lubricant. Its high quality formula helps rapidly attain ideal vaginal lubrication. Glide™ can safely and effectively be used with Zestra®. Glide does not contain medicated ingredients and is used to lubricate the vaginal area. It will not provide the same effect as Zestra® patented topical oil.